Not known Factual Statements About sodium pentobarbital
Not known Factual Statements About sodium pentobarbital
Blog Article
pentobarbital decreases effects of hemin by pharmacodynamic antagonism. Use Warning/Check. Drugs that improve delta-aminolevulinic acid synthetase may well reduce hemin effect.
pentobarbital will decrease the extent or effect of budesonide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Animal facts. Phenobarbital sodium is carcinogenic in mice and rats right after lifetime administration. In mice, it created benign and malignant liver mobile tumors. In rats, benign liver cell tumors had been noticed very late in life.
4. Compatible with death in aged or unwell persons or in presence of obstructed airway, other poisonous agents, or exposure to cold.
Contraindicated (1)pentobarbital decreases amounts of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Sturdy CYP3A4 inducers can cut down panobinostat stages by ~70% and produce cure failure.
pentobarbital will reduce the level or effect of ondansetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. No dosage adjustment for ondansetron is recommended for patients on these drugs.
pentobarbital raises toxicity of ifosfamide more info by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. CYP3A4 inducers may raise the metabolism of ifosfamide to its Energetic alkylating metabolites.
pentobarbital will minimize the extent or effect of almotriptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lower the extent or effect of voriconazole by influencing hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Unfamiliar.
pentobarbital will decrease the level or effect of vincristine liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.
pentobarbital will lessen the extent or effect of celecoxib by affecting hepatic enzyme CYP2C9/ten metabolism. Insignificant/Significance Unknown.
pentobarbital will decrease the level or effect of clarithromycin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
pentobarbital will minimize the level or effect of ixabepilone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the extent or effect of cilostazol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.